The key matchup here is Matheus Cunha against Brentford's backline, especially Kristoffer Ajer. Cunha has been directly involved in 15 goals this season for Wolves, a bright spot in what's been a tough year.
Brentford, meanwhile, have won only one of their last five Premier League matches, a 2-0 victory over Sheffield United. That's not exactly inspiring form. Wolves, on the other hand, just got thumped 5-1 by Manchester City, but they've shown flashes of competence at home this season, including a win over Tottenham.
This one feels like a scrappy affair. I'm going with Wolves to grind out a 2-1 victory.
Predictions are for entertainment purposes only. Not gambling advice.